Eight rooms in a neoclassical mansion of about 150 years on Apollonos Street, near Vaporia, home in turn to the Negreponte, Samios and Lorentzos families and a hotel since 2008. Venetian chandeliers, handmade rugs and marble bathrooms, and a paved terrace with sunbeds that leads straight down into the sea. Open April to October.
Suites in a protected 19th-century neoclassical building on Apollonos Street, five storeys high with its foundations in the sea, restored in 2009 to its original architecture.
Forty rooms in a 19th-century building on Papagou Square, right on the port. In its time it has been a store for wood, coal and tobacco, a tannery, a cabaret and, in the Occupation, the Italian military police headquarters; a hotel since 1980, renovated in 2015. The handiest bed for an early ferry.
A classic town hotel by the sea near the port, renovated in 2010 and open all year, with 42 rooms and two suites. The sea-view rooms look across to Tinos and Mykonos, the others up to the two hills of Ano Syros and Vrontado. Buffet breakfast included.
Renovated rooms on Iroon Square, about 350 m from the port, with a bus stop to the beaches outside the door. Every room has a balcony, and some look up at both of the town's hills, Catholic Ano Syros and Orthodox Anastasi. A simple, central and good-value base.
Rooms on the hill of Ano Syros, named for the windmill beside them, high above Ermoupoli and the harbour, a short walk from the medieval lanes and the cathedral of San Giorgio.
Six suites on the little hill of Lotos above Kini, around a family house built over the wine cellar of Marin Rigouzzo, the owners' great-grandfather and once consul of France and Belgium, who sat here under a pine that is about 150 years old. A guesthouse since 2007, with a bar for breakfast and drinks, and the sunset in front.
Family-run rooms and apartments with terraces over a flower garden in Kini, a minute or two from the beach, with a mini-market and the bus to Ermoupoli close by. Quiet, spotless and much praised for its hosts.
A Cycladic-style hotel next to Fetouri beach in Posidonia, with doubles, triples and family rooms, a restaurant and bar, and the old merchants' villas of Dellagrazia a short walk away.
A family-run hotel right on the sand of Vari bay, 7 km from Ermoupoli, known for its home cooking and its sheltered, shallow water, which makes it a good choice with children.